Document Type : Original Article
Authors
1
Department of Microbiology and Immunology, National Research Centre ,Dokki, Giza, Egypt
2
Hydrobiology Department, Veterinary Research Division, National Research Centre, El Buhouth St., Dokki, 12311 Cairo (Egypt)
3
National Research Center
4
Department of virology, Faculty of Veterinary medicine,university of Sadat city, Sadat city,Menoufia: Egypt.
5
Microbiology and Immunology Dept., Vet. Research Div., NRC, Egypt
6
Department of Animal Hygiene and Zoonoses, Faculty of Veterinary Medicine, university of sadat city, Egypt.
7
Department of zoonotic diseases. National Research Centre. Post Box 12622, ‎Elbohouth str.Dokki.Cairo, Egypt.‎
8
Department of Virology, Faculty of Veterinary Medicine, University of Sadat City
Abstract
An effective substitute for the conventional virus control techniques used by the poultry business is the supplementation of herbal plants (cheap, naturally available and less toxic) in chicken diets. Application of them has been associated with notable improvements in the immunity and performance of birds. 180 cobb chicks were split into six equal-sized groups for the present study. A group A was left as a negative group, two groups (groups B and C) were left as control positive non-vaccinated infected group and control positive vaccinated infected group, respectively. Groups (groups D, E, and F) received an injection of vNDV strain associated with the ND Clone 30 vaccine and live LaSota vaccine and treated with medicinal herbs. The performance of the birds is enhanced by oral administration of Nigella sativa (6%), commercial curcumin® (1%), and Orego sol.®. All infected chicks secreted virus through trachea and cloaca, but the pattern differed among different groups. The chicks in group B showed more significant virus secretion. Similarly, increased expression of cytokine genes promotes immunostimulation action in different groups, leading to the reduction of NDV pathogenesis. When chicks were given Orego sol.®, there was a greater evident reduction in viral shedding and an improvement in their immune responses.
Keywords
Main Subjects
)
View on SCiNiTO