Pathogenicity of Coagulase Negative Staphylococcus chicken isolates to 10 Days Old Broiler Chickens

Shokry, Mariam Hussien; Bosila, Mohamed; Abd El-Ghany, Wafaa A.; Redwan, Ismail Abdelhafeez; Amer, Mohamed Mahrous

doi:10.21608/ejvs.2018.3280.1035

Pathogenicity of Coagulase Negative Staphylococcus chicken isolates to 10 Days Old Broiler Chickens

Document Type : Original Article

Authors

¹ Faculty of Veterinary medicine, Cairo University

² Dept of Poultry. Diseases, Vet. Res. Division, National Research centre

³ Professor of Poultry Diseases Faculty of Veterinary Medicine, Cairo University

⁴ Professor and head of Bacteriology , Mycology and Immunology Department, Faculty of Veterinary Medicine, Bani-suif University

⁵ Poultry and Rabbit disease Department/Faculty of veterinary medecine / Cairo University

10.21608/ejvs.2018.3280.1035

Abstract

One hundred and sixty, 1-day old broiler chicks were grouped into 4 equal groups, at the 10^th day birds of groups 1- 3 were s.c inoculated with 0.5 ml containing y 1.5x 10⁸ of S.xylosis, S. sciuri and S.lentus; respectively and group 4 was noninfected control.
Clinical signs in infected groups started at 2-3dpi as general signs. Signs disappear in Ciprofloxacillin treated subgroups 24 hr post treatment and lasted to the 7^th day in non treated.
Average body weight gain in S.xylosis infected non treated was the highest (813.90 gm), followed by S. scuiri (778.50gm ) and 773.75 in S. lentus infected treated . FCR was the highest in control (1.69 treated and 1.74 non treated) followed by S. scuiri infected (1.81 non treated and 1.82 treated) and the lowest 1.94 was in S.lentus infected non treated. S. sciuri was reisolated from intestine and spleen (5^th dpi) and from intestine (7 and 10 dpi). While S.lentuswas reisolated from intestine , liver and spleen (3^rd dpi) ; from intestine and spleen (5^th dpi) and intestine (10^th dpi).
Histopathological lesion was recorded in infected group as hemorrhages with sinusoidal dilation, focal areas of vacuolar degeneration , fatty degeneration and shrinkage of hepatocytes in liver, necrotic changes of lymphocytes and vacuolion of corpuscle in spleen. Leucocytic infiltration , degeneration and necrosis of epithelium surface and intraepithelial as well as submucosal leucoytic infiltration were seen in intestine.
In conclusion the injected organisms induce mild subclinical disease with recording of histopathological lesions in liver, spleen and intestine. This area needs more investigation to explore pathogenicity of CoNS in chickens.

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