Metabolic Profiling 10 Weeks Before Until 25 Weeks After Parturition in Dairy Cows

Document Type : Original Article

Authors

1 Department of Clinical Sciences, College of Veterinary Medicine, Qassim University, P.O. Box 6622, Buraidah, 51452, Saudi Arabia

2 Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura-City, 35516, Egypt. Department of Veterinary Surgery, Salam Veterinary Group, Buraydah, Qassim, Buraidah, 51452, Saudi Arabia.

Abstract

The experiment was planned to monitor the metabolic status of the dairy cows from 10 weeks before until 25 weeks after parturition. For this purpose, 10 clinically healthy multiparous pregnant were used. Twelve blood samples and subsequently sera were collected from each cow as follows: before expected parturition at -10wk, -7wk, and -3wk, within 12 hours of parturition, and after parturition at weeks 1, 2, 3, 4, 5, 10, 15 and 25. Compared to values at 10wk before parturition, the BW increased significantly at 3wk. However, BW decreased significantly at -10wk and at -3wk. The AST activity increased significantly at parturition compared to -10wk activity; it remained high through weeks 1,2,3,4 and 10 after parturition. The total bilirubin concentration increased gradually starting from -3wk before the expected parturition until 1wk after parturition, then decreased gradually until 15wk after parturition with a statistical difference compared to values at parturition. Starting from -10wk before parturition, total cholesterol concentration decreased significantly until birth then increased gradually until 10wk after parturition. The concentration of non-esterified fatty acids increased substantially at birth and 1 week after parturition compared to tested weeks before birth. The levels were also high at 4wk, 5wk, and 10wk after birth compared to tested weeks before parturition. The triglyceride concentration increased significantly at -7wk and -3wk compared to -10wk before parturition. In conclusion, the metabolic profiling test is a prognostic indicator of the healthy condition of dairy cows during a long period that extends almost 250 days of different reproductive phases. 

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Articles in Press, Corrected Proof
Available Online from 23 January 2025
  • Receive Date: 30 November 2024
  • Revise Date: 18 January 2025
  • Accept Date: 18 January 2025