Efficacy of Rosmarinus officinalis L. and FeCl3 Extracts on Some Biochemical Parameters during Treatment of Epilepsy in Male Rats Models

Document Type : Original Article

Author

Northern Technical University

Abstract

The research methodology included evaluating changes in antioxidants and fat oxide levels. Sixty (60) male mice were divided into six groups: control (no additional treatment), FECL3 group, and four groups managed with different components of Rosmarinus Officinalis L. (flavonoid, glycoside, and alkaloids). Show the results,  elevated levels of β-secretase, Na, and K in the FeCl3 group and the groups receiving Rosmarinus officinalis L. components. Conversely, compared to the FeCl3 group, those administered with Rosmarinus officinalis L. components exhibit levels of Fucose, Invins-C, and Zn. In terms of oxidant enzyme activity and the lithe oxidation, the FeCl3 group showed significant increases in GSH, MDA, SOD, and CAT compared to the control group. However, the Rosmarinus officinalis L. components resulted in elevated levels of MDA and SOD, along with reduced GSH and CAT levels. In conclusion, the components extracted from Rosmarinus officinalis L. β-securecuresed effects on β-Secretase, Fucose, and Voxidantts, in addition to modulating antioxidant activity and lipid peroxidation constituent’s sartivevcenreduces the costolesfficinalis L. active constituents The aim of the a novel class of anti-epileptic medications. 

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