Histological Study of Antibiotic Effect on Liver, Kidney and Breast Muscle in Poultry

Khatlan Hameed, Bader; Adil Hameed, Marwa; Hussein, Hadeel Mahdi; Agmee Wadee, Siham

doi:10.21608/ejvs.2024.250672.1680

Histological Study of Antibiotic Effect on Liver, Kidney and Breast Muscle in Poultry

Document Type : Original Article

Authors

¹ Department of Anatomy and Histology, College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq

² 2Department of Physiology, Pharmacology and Biochemistry, College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq

³ Department of Physiology, Pharmacology and Biochemistry, College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq

10.21608/ejvs.2024.250672.1680

Abstract

Veterinarians and the poultry industry utilize antibiotics to improve the health and growth rates of birds, and increase egg output, feed efficiency, and the frequency of illnesses in poultry. The Antibiotic used for preventative and therapeutic purpose. the illicit use of these medications has resulted in the build-up of harmful poultry products containing antibiotics residue that are intended to conception of human. , there is serious risk occurring in the community from this microbiological, immunological, or toxicological.
The study was conducted to demonstrate the effect antibiotics on the histological effect (Liver, Kidney and Breast muscle) 300 chicken used and divided into two groups.
Group(A): chicken are aged 38 day and subdivide into three subgroups, first ciprofloxacin age 20 day second with colistin in age 30 day third in age 5 days neomycin .
Group (B): chicken are aged 42 day and subdivided into two subgroups, first used colistin and tylosin antibiotics in age 13 day for and second group used erythromycin in age 20 day for .the dose of antibiotic 5-15 mg \kg of BW. when chickens were killed, a tissue sample was taken
Outcome includes effects on the kidney, glomerular atrophy and reduction of convoluted tubule epithelial cells. Hemolysis in blood vessels, while in liver caused cell degradation.results showed an impact on the breast muscle that led to nerve fiber degeneration and muscle fiber atrophy. The aim of the study was to investigate the histopathological effects of antibiotic residues on various bird tissues and potential health risks for humans.

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