Effects of Urtica dioica Hydroalcoholic Extract on The urinary Tract of Broilers

Document Type : Original Article

Authors

1 Department of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.

2 Poultry disease specialist of Iran veterinary organization, Qom office, Qoam ,Iran.

3 Agriculture and Natural Resources Research Center of Qom, Qom, Iran

4 School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, Australia; Graham Centre for Agricultural Innovation (NSW Department of Primary Industries and Charles Sturt University), Wagga Wagga, Australia.

5 poultry vaccine research and production Department, Razi Vaccine and Serum Research Institute, Agricultural research, Education and Extension, Karaj,Iran.

6 Research and Development unit of Barij Essence Pharmaceutical Company, Kashan, Iran.

Abstract

Poultry breeders knew nettle and used poultry feed for long time but so far no research has been done on its diuretic effects in broilers particulary as field trail. In order to investigate the effects of nettle (Urtica dioica) hydroalcoholic extract on urinary track of broilers, a broiler farm with renal disorders was selected and the study was carried out as a field trial. The capacity of each shed was 10,000 broilers (Ross’s commercial breed strain).  At the age of 18 days-old, two sheds that had renal disorders with clinical mortality. In gross pathology gout, and urolithiasis was noted. Nettle (Urtica dioica) hydroalcoholic extract and one commercial drug (Urotropin) were used in this study for three days.Weightgain, mortality rate, macroscopic and microscopic examination, serum biochemical factors (urea, ceratinine, uric acid, calcium and phosphorus) were evaluated before and after treatments in both sheds. The results were analyzed using SPSS software. The results showed at the end of treatment, the nephrotic complication was significantly less (p= 0.4 and p= 0.04) and microscopic observations significantly decreases (p=0.16 and p = 0.32)  in the herd treated with nettle extract respectively. Also, in biochemistry examinations there was no significant difference in the level of urea, creatinine, calcium and phosphorus of the two herds at the end of drug therapy (p= 0.07, p = 0.3, p = 0.3 and p= 0.26), but at the end of the treatment, the amount of uric acid treatment with nettle extract was significantly lower than that of the urotropin treated herd (p= 0.004).Therefore, in general, the results of this study conducted that the administration of a hydroalcoholic extract of nettle with a dose of 1 in 1000 in poultry drinking water on kidney complications had more effective results than administration of urotropin.


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