Comparative Insights into Haematopoiesis: Blood Cell Development in Fish and Vertebrates

Mansour, Mohamed Mostafa; Badran Shoeib, Mahmoud Mohamed; Mohamed Morsi, Safwat Ebada; El-Sayed Yousse, Galal Ahmed; El-Sayed, Mesbah Abd El-Gawad

doi:10.21608/ejvs.2025.325423.2474

Comparative Insights into Haematopoiesis: Blood Cell Development in Fish and Vertebrates

Articles in Press

Document Type : Review Artical

Authors

¹ Anatomy and embryology department, faculty of veterinary medicine , Mansoura university , Egypt

² Department of Anatomy and Embryology Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt

10.21608/ejvs.2025.325423.2474

Abstract

Haematopoiesis is a crucial biological process that produces and enhances red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs). HSCs possess a unique capacity to self-renew and differentiate into a high number of progenitor cells. The pronephros, also known as the "head kidney" in fish, is a critical hematopoietic organ, similar to bone marrow in mammals. identifies a system that helps create and maintain blood cells and is found in all vertebrate animals. Evolutionary parallels between fish and mammal hematopoietic processes not only indicate the functional homogeneity of blood systems, but also provide prospective areas for more focused investigations on blood cell biology in a number of species.

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